(4R-CIS)-1,1-Dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]- 1h-pyrrol-1-ylethyl]-2,2-dimethyl-1,3-dioxane-4-acetate (L1)
- CasNo:125971-95-1
Product Description
Quality products?make an important contribution to long-term revenue and profitability. Bulk supply high purity (4R-CIS)-1,1-Dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]- 1h-pyrrol-1-ylethyl]-2,2-dimethyl-1,3-dioxane-4-acetate (L1) 125971-95-1, Paid sample available
1.What is the tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate ?
Atorvastatin Acetonide tert-Butyl Ester (Atorvastatin EP Impurity I) is an Atorvastatin intermediate.
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1331869-19-2
C26 H22 FNO3
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![tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate](/upload/2026/4/2ecf9d7157b94f1193058bc0fc960dab_08ab8528-6177-4863-b451-3b1ef0bf1816.png)
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125971-86-0,125995-13-3
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
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![tert-butyl (4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxane-4-acetate](/upload/2026/4/a84edb0b7c5c4e869d871b972999e628_55681638-6467-4c6e-b274-57b08ac753f1.png)
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125971-95-1
tert-butyl (4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxane-4-acetate
| Conditions | Yield |
|---|---|
|
With
1,8-diazabicyclo[5.4.0]undec-7-ene; Trimethylacetic acid;
In
cyclohexane;
at 80 - 84 ℃;
for 25h;
Concentration;
Reagent/catalyst;
Dean-Stark;
Reflux;
|
79%
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; hexane; toluene;
at 110 ℃;
for 30h;
Inert atmosphere;
|
-
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125971-86-0,125995-13-3
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
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![2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide](/upload/2026/4/d1185a250be94a0d8e17904e0b054031_21e8e987-4764-447f-86a6-efc0ff3eceb8.png)
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125971-96-2,125971-58-6
2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
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125971-95-1
tert-butyl (4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxane-4-acetate
| Conditions | Yield |
|---|---|
|
With
Trimethylacetic acid;
In
toluene;
at 105 - 110 ℃;
for 1h;
Industrial scale;
|
96.5%
|
|
With
tetra(n-butyl)ammonium hydrogensulfate; diisopropylamine; Trimethylacetic acid;
at 78 - 85 ℃;
for 40h;
|
82.3%
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
Heating;
|
75%
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran;
for 40 - 72h;
Heating / reflux;
|
75.1%
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
for 48h;
Heating / reflux;
|
72.3%
|
|
With
tetra(n-butyl)ammonium hydrogensulfate; Trimethylacetic acid;
at 120 ℃;
for 5.5h;
Temperature;
Reagent/catalyst;
|
69.6%
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
Heating;
|
|
|
triethylamine; Trimethylacetic acid;
In
tetrahydrofuran; hexane;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
hydrogenchloride; triethylamine;
In
tetrahydrofuran; tert-butyl methyl ether;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
triethylamine; Trimethylacetic acid;
In
tetrahydrofuran; tert-butyl methyl ether;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
N-ethyl-N,N-diisopropylamine; Trimethylacetic acid;
In
toluene;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
sodium hydroxide; Trimethylacetic acid;
In
toluene;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
sodium hydroxide; Trimethylacetic acid;
In
tetrahydrofuran; tert-butyl methyl ether;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
zinc diacetate;
In
tetrahydrofuran; tert-butyl methyl ether;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
N-ethylmorpholine;; Trimethylacetic acid;
In
toluene;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
calcium hydroxide; Trimethylacetic acid;
In
tetrahydrofuran; tert-butyl methyl ether;
at 50 ℃;
Product distribution / selectivity;
Heating / reflux;
|
|
|
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide;
In
cyclohexane;
at 25 - 30 ℃;
for 0.25 - 0.333333h;
With
Trimethylacetic acid;
In
cyclohexane;
Heating / reflux;
|
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; hexane;
at 75 ℃;
for 96h;
Product distribution / selectivity;
|
|
|
With
Trimethylacetic acid;
In
cyclohexane;
at 20 ℃;
Heating / reflux;
|
|
|
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide;
Trimethylacetic acid;
In
tetrahydrofuran; cyclohexane;
at 25 - 85 ℃;
for 18h;
Heating / reflux;
With
ammonia;
In
tetrahydrofuran; cyclohexane; water;
at 20 - 35 ℃;
for 0.833333h;
pH=8.5 - 9.5;
|
|
|
Trimethylacetic acid;
In
2-methyl THF;
for 30 - 35h;
Heating / reflux;
|
|
|
With
Trimethylacetic acid;
In
cyclohexane; isopropyl alcohol;
|
|
|
With
Trimethylacetic acid;
In
cyclohexane;
at 20 - 78 ℃;
|
|
|
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide;
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
for 40h;
Heating / reflux;
With
sodium hydroxide;
In
tetrahydrofuran; n-heptane; water; toluene;
With
hydrogenchloride;
In
tetrahydrofuran; n-heptane; water; toluene;
|
|
|
tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide;
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
for 40h;
Heating / reflux;
With
sodium hydroxide;
In
tetrahydrofuran; n-heptane; water; toluene;
With
hydrogenchloride;
In
tetrahydrofuran; n-heptane; water; toluene;
|
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
for 40h;
Heating / reflux;
|
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane; toluene;
for 40h;
Heating / reflux;
|
|
|
With
Trimethylacetic acid;
In
n-heptane;
at 100 ℃;
|
|
|
|
|
|
With
2,2-dimethylpropanoic anhydride;
In
2-methyltetrahydrofuran;
at 150 ℃;
for 4h;
Temperature;
Autoclave;
Inert atmosphere;
Green chemistry;
|
65 g
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; toluene;
Reflux;
|
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; n-heptane;
for 60h;
Reflux;
|
|
|
With
Trimethylacetic acid;
In
tetrahydrofuran; hexane; toluene;
Reflux;
|
2.What is the CAS number for tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate ?
The CAS number of tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate is 125971-95-1.
More information of tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate 125971-95-1 are:
|
CAS?Number |
125971-95-1 |
|
Density |
1.15 g/cm3 |
|
Melting Point |
144-148 °C |
|
Boiling Point |
678.035 °C at 760 mmHg |
|
Flash Point |
363.863 °C |
|
HS CODE |
29349990 |
|
PSA |
78.79000 |
|
LogP |
9.44200 |
|
Pka |
13.57±0.70(Predicted) |
3.What are another words for tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate ?
Synonyms?for?tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate 125971-95-1:1,3-Dioxane-4-aceticacid,6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-,1,1-dimethylethyl ester, (4R-cis)-;(4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate(L-1);1,3-Dioxane-4-aceticacid,6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-,1,1-dimethylethyl ester, (4R,6R)-;
4.What is the molecular formula of tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate?
The chemical formula of ?tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate is?C40H47FN2O5 which containing 40 Carbon atoms,47 Hydrogen atoms,1 Fluorine atoms,2 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight of??tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate?is 654.822.
5.What is tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate (125971-95-1) used for?
tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate is a complex organic compound with a unique molecular structure. It is characterized by its white solid appearance and is primarily used as an intermediate in the synthesis of Atorvastatin, a widely prescribed medication for lowering cholesterol levels.
InChI:InChI:1S/C40H47FN2O5/c1-26(2)36-34(27-14-10-8-11-15-27)35(38(45)42-30-16-12-9-13-17-30)37(28-18-20-29(41)21-19-28)43(36)23-22-31-24-32(47-40(6,7)46-31)25-33(44)48-39(3,4)5/h8-21,26,31-32H,22-25H2,1-7H3,(H,42,45)
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6.Buy tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate with the best price .
Hangzhou World-wide Biology Tech Co.ltd is a quality supplier of tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate 125971-95-1.