(1-(2-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol

(1-(2-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol GMP Manufacturer Global Trade 114798-26-4 with Fast Delivery We provide high quality Losartan (CAS 114798-26-4), at a very affordable prices to our customers.

1.What is the Losartan ?

Losartan, also known as Cozaar, is a nonpeptide angiotensin II AT1-receptor antagonist. It is an orally active compound with high specificity for the AT1 receptor. Losartan undergoes extensive first-pass metabolism, with the 5-methanol being oxidized to a carboxylic acid, mediated by CYP 2C9 and 3A4 isozymes. The 5-methanol metabolite is approximately 15 times more potent than the parent hydroxyl compound. Losartan is a biphenylyltetrazole with a 1,1'-biphenyl group attached at the 5-position and an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position.

antihypertensive;antagonist of angiotensin type 1

2.What is the CAS number for Losartan ?

The CAS number of Losartan is 114798-26-4.

More information of Losartan 114798-26-4 are:

3.What is the molecular formula of Losartan ?

The chemical formula of?Losartan is C22H23ClN6O which containing 22 Carbon atoms,23 Hydrogen atoms,1 Chlorine atoms,6 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight, and the molecular weight of Losartan is 422.917

4.What is Losartan(114798-26-4)used for?

Losartan, also known as Cozaar, is a nonpeptide angiotensin II AT1-receptor antagonist. It is an orally active compound with high specificity for the AT1 receptor. Losartan undergoes extensive first-pass metabolism, with the 5-methanol being oxidized to a carboxylic acid, mediated by CYP 2C9 and 3A4 isozymes. The 5-methanol metabolite is approximately 15 times more potent than the parent hydroxyl compound. Losartan is a biphenylyltetrazole with a 1,1'-biphenyl group attached at the 5-position and an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position.

InChI:InChI=1/C22H23ClN6O/c1-2-3-9-20-24-21(23)19(14-30)29(20)13-15-10-11-17(16-7-5-4-6-8-16)18(12-15)22-25-27-28-26-22/h4-8,10-12,30H,2-3,9,13-14H2,1H3,(H,25,26,27,28)

Relevant articles related to Losartan:

5.(1-(2-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol GMP Manufacturer Global Trade 114798-26-4 with Fast Delivery

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