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Empagliflozin crude

  • CasNo:864070-44-0

Product Description

Quality manufacturer supply Empagliflozin crude 864070-44-0 in stock with high standard We supply high quality Empagliflozin (CAS 864070-44-0), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Empagliflozin ?

Empagliflozin is , while it's Molecular Formula is C23H27ClO7 . Empagliflozin is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.

What is the CAS number for Empagliflozin ?

The CAS number of Empagliflozin is 864070-44-0.

More information of Empagliflozin 864070-44-0 are:

Synonyms

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxyMethyl)-tetrahydro-2H-pyran-3,4,5-triol;Empaglifloin;Glyxambi;mpagliflozin;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol;ozin;Empag;CS-798;EmpagL;BI-10773

CAS?Number

864070-44-0

Molecular Formula

C23H27ClO7

Molecular Weight

450.916

Density

1.398

Boiling Point

665℃

Flash Point

356℃

PSA

108.61000

LogP

1.61340

Pka

13.23±0.70(Predicted)

What is Empagliflozin (864070-44-0) used for?

Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, was originally discovered by Boehringer Ingelheim and codeveloped and co-marketed through research collaboration with Eli Lilly and Co. It was first approved by European Medicine Agency (EMA) in May 2014, followed by the approval of the US FDA in August 2014. SGLT2 inhibitors are anewclass of glucose-lowering agents developed for the treatment of type 2 diabetes mellitus, which have a mechanism of action that is independent of pancreatic b-cell function or the degree of insulin resistance. Consequently, SGLT2 inhibitors have the potential to be of use not only as standalone therapy but also in combination with any of the existing classes of glucose-lowering agents, including insulin. Empagliflozin selectively inhibits SGLT2, which in turn prevents glucose reabsorption by excreting excess glucose in the urine.

Articles related to Empagliflozin:

Article

Source

IMPROVED PROCESS FOR THE PREPARATION OF EMPAGLIFLOZIN AND ITS CRYSTALLINE POLYMORPH

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, (2021/12/31)

Synthetic method of empagliflozin

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Paragraph 0039; 0041-0042; 0044, (2021/10/30)

How to get the best price on Empagliflozin?

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