2-[(2R)-2-Hydroxy-3-[[4-(3-0xomorpholin-4-yl)phenylamino]propyl]-1H-isoindole-1,3(2H)-dione
- CasNo:446292-07-5
Product Description
Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply high quality 2-[(2R)-2-Hydroxy-3-[[4-(3-0xomorpholin-4-yl)phenylamino]propyl]-1H-isoindole-1,3(2H)-dione 446292-07-5 with ISO standards
1.What is the 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- ?
Rivaroxaban intermediate.
-
![4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one](/upload/2026/4/4569cbd7fb384119a3722de8a9c001d4_18b84c26-5e6f-4be9-a2fd-3831d222bb4f.png)
-
1252018-10-2
4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one
-
-
1074-82-4
potassium phtalimide
-
![2-((2S)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione](/upload/2026/4/a68deaa45548418faf4f52743e4e924e_c4cb80d2-7315-4b36-afaa-10cd9ab5502e.png)
-
446292-07-5
2-((2S)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione
| Conditions | Yield |
|---|---|
|
In
N,N-dimethyl-formamide;
at 20 - 100 ℃;
for 3h;
|
93%
|
|
4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one;
With
sodium hydroxide;
In
dichloromethane; water;
at 20 ℃;
for 8h;
potassium phtalimide;
In
1,4-dioxane;
at 100 ℃;
for 3h;
Reagent/catalyst;
|
92%
|
|
In
methanol;
for 10h;
Concentration;
Reflux;
|
87.8%
|
|
In
methanol;
for 9h;
Reflux;
|
87.8%
|
|
In
N,N-dimethyl-formamide;
for 5h;
|
|
|
In
methanol;
for 10h;
Concentration;
Reflux;
|
51.4 g
|
-
-
161596-47-0
(S)-N-glycidylphthalimide
-
-
438056-69-0
4-(4-aminophenyl)morpholin-3-one
-
-
446292-07-5
2-((2S)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione
| Conditions | Yield |
|---|---|
|
In
ethanol; water;
at 20 ℃;
for 15h;
Solvent;
Temperature;
|
95%
|
|
In
ethanol; water;
for 27h;
Heating;
|
92%
|
|
In
methanol; water;
at 65 - 70 ℃;
for 32h;
|
92%
|
|
In
ethanol;
for 10h;
Reflux;
|
92%
|
|
In
ethanol; water;
for 14h;
Reflux;
|
89.7%
|
|
In
isopropyl alcohol;
for 16h;
Reflux;
|
89.3%
|
|
In
water; isopropyl alcohol;
at 25 ℃;
for 24h;
Reflux;
|
87.5%
|
|
In
methanol;
for 24h;
Reflux;
|
87.5%
|
|
In
water; isopropyl alcohol;
Reflux;
|
82.6%
|
|
In
water; isopropyl alcohol;
Reflux;
|
82.6%
|
|
In
methanol;
at 0 - 60 ℃;
for 20h;
Large scale;
|
82.7%
|
|
In
ethanol; water;
at 20 - 60 ℃;
for 36h;
|
81.4%
|
|
In
ethanol; water;
at 20 - 60 ℃;
for 36h;
|
81.4%
|
|
In
ethanol; water;
Reflux;
|
81.62%
|
|
In
ethanol;
at 80 ℃;
for 9h;
|
80.68%
|
|
With
water;
In
ethanol;
at 60 ℃;
for 36h;
Industry scale;
|
75.4%
|
|
at 75 - 80 ℃;
for 18h;
|
|
|
In
ethanol;
at 75 - 80 ℃;
for 18h;
|
|
|
In
water;
at 80 ℃;
for 8h;
|
203 g
|
|
With
water;
at 75 - 80 ℃;
for 5h;
Temperature;
Large scale;
|
|
|
In
ethanol; water;
at 65 ℃;
for 6h;
|
12.3 g
|
2.What is the CAS number for 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- ?
The CAS number of 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- is 446292-07-5.
More information of 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 446292-07-5 are:
|
CAS?Number |
446292-07-5 |
|
Density |
1.421 g/cm3 |
|
Melting Point |
208-211°C |
|
Boiling Point |
734.905 °C at 760 mmHg |
|
Flash Point |
398.256 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.672 |
|
HS CODE |
2922498590 |
|
PSA |
99.18000 |
|
LogP |
1.19470 |
|
Pka |
13.91±0.20(Predicted) |
3.What are another words for 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- ?
Synonyms?for?1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 446292-07-5:4-[((2R)-Hydroxy-3-phthaliMido)propylaMine]phenyl-3-Morpholinone
4.What is the molecular formula of 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-?
The chemical formula of ?1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- is?C21H21N3O5 which containing 21 Carbon atoms,21 Hydrogen atoms,3 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight of??1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-?is 395.415.
5.What is 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- (446292-07-5) used for?
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]is a complex organic compound characterized by its unique molecular structure. It is a white solid with specific chemical properties that make it a valuable intermediate in the synthesis of pharmaceutical compounds.
InChI:InChI=1/C21H21N3O5/c25-16(12-24-20(27)17-3-1-2-4-18(17)21(24)28)11-22-14-5-7-15(8-6-14)23-9-10-29-13-19(23)26/h1-8,16,22,25H,9-13H2/t16-/m1/s1
Relevant articles related to 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-:
|
Article |
Source |
|
Oxazolidinone derivative and preparation method thereof |
- Paragraph 0018, (2020/03/05) |
|
Preparation method of rivaroxaban intermediate |
- Paragraph 0023; 0024, (2020/04/17) |
6.Buy 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- with the best price .
Hangzhou World-wide Biology Tech Co.ltd is a quality supplier of 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 446292-07-5.