5-[(4-Ethyl-1-pperazinyl)methyl]-2-pyridinamine
- CasNo:1180132-17-5
Product Description
Quality products?make an important contribution to long-term revenue and profitability. Reputable factory supply 5-[(4-Ethyl-1-pperazinyl)methyl]-2-pyridinamine 1180132-17-5 in bulk at low price
1.What is the 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine ?
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine is a useful research chemical.
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-
33225-73-9
6-nitronicotinic acid
-
-
1180132-17-5
5-((4-ethylpiperazin-1-yl)methyl)-6-methylpyridin-2-amine
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
3
steps
1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 2.5 h / 0 - 25 °C
2: palladium 10% on activated carbon; hydrogen / methanol; water / 2 h / 50 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C / Inert atmosphere
With
lithium aluminium tetrahydride; palladium 10% on activated carbon; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
|
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-
5308-25-8
4-ethylpiperazine
-
-
69879-22-7
6-amino-3-pyridinecarbaldehyde
-
-
1180132-17-5
5-((4-ethylpiperazin-1-yl)methyl)-6-methylpyridin-2-amine
| Conditions | Yield |
|---|---|
|
With
sodium tris(acetoxy)borohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 10h;
|
91%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
1,2-dichloro-ethane;
at 20 ℃;
for 2h;
With
sodium tris(acetoxy)borohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 8h;
|
91%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
1,2-dichloro-ethane;
at 20 ℃;
for 2h;
With
sodium tris(acetoxy)borohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 8h;
|
91%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
1,2-dichloro-ethane;
at 20 ℃;
for 2h;
With
sodium tris(acetoxy)borohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 8h;
|
84%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
1,2-dichloro-ethane;
at 20 ℃;
for 2h;
With
sodium tris(acetoxy)borohydride;
at 20 ℃;
for 8h;
|
84%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
1,2-dichloro-ethane;
at 20 ℃;
for 2h;
With
sodium tris(acetoxy)borohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 8h;
|
84%
|
|
4-ethylpiperazine; 6-amino-3-pyridinecarbaldehyde;
In
methanol;
at 20 ℃;
for 1h;
With
sodium cyanoborohydride;
In
methanol;
at 20 ℃;
for 15h;
|
800 mg
|
|
With
formic acid;
In
acetonitrile;
at 80 ℃;
|
2.What is the CAS number for 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine ?
The CAS number of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine is 1180132-17-5.
More information of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 1180132-17-5 are:
|
CAS?Number |
1180132-17-5 |
|
Density |
1.101 |
|
Boiling Point |
362℃ |
|
Flash Point |
173℃ |
|
HS CODE |
2933990090 |
|
PSA |
46.12000 |
|
LogP |
0.60720 |
|
Pka |
7.71±0.10(Predicted) |
3.What are another words for 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine ?
Synonyms?for?5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 1180132-17-5:5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-ylamine;5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-amine;
4.What is the molecular formula of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine?
The chemical formula of ?5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine is?C12H20N4 which containing 12 Carbon atoms,20 Hydrogen atoms and 4 Nitrogen atoms,and the molecular weight of??5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine?is 220.318.
5.What is 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine (1180132-17-5) used for?
Relevant articles related to 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine:
|
Article |
Source |
|
Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma |
Yuan, Kai,Kuang, Wenbin,Chen, Weijiao,Ji, Minghui,Min, Wenjian,Zhu, Yasheng,Hou, Yi,Wang, Xiao,Li, Jiaxing,Wang, Liping,Yang, Peng supporting information, (2021/12/09) |
|
Sustainable synthesis of potential antitumor new derivatives of Abemaciclib and Fedratinib via C-N cross coupling reactions using Pd/Cu-free Co-catalyst |
Khorsandi, Zahra,Keshavarzipour, Fariba,Varma, Rajender S.,Hajipour, Abdol R.,Sadeghi-Aliabadi, Hojjat , (2021/11/24) |
6.Buy 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine with the best price .
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