3-Amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
- CasNo:330792-70-6
Product Description
Quality manufacturer supply 3-Amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6 in stock with high standard
- Molecular Formula: C16H12N4O
- Molecular Weight: 276.297
- Boiling Point: 585.3±50.0 °C(Predicted)
- PKA: 10.83±0.50(Predicted)
- PSA: 88.45000
- Density: 1.37±0.1 g/cm3(Predicted)
- LogP: 3.25298
330792-70-6 Relevant articles
Regioselective Synthesis of Highly Functionalized Pyrazoles from N-Tosylhydrazones
Zhang, Qian,Tang, Meng
supporting information, (2019/03/19)
A regioselective synthesis of highly fun...
Therapeutic Combinations of a Proteasome Inhibitor and a BTK Inhibitor
-
, (2019/07/23)
Therapeutic combinations of a proteasome...
TREATMENT OF INDOLENT OR AGGRESSIVE B-CELL LYMPHOMAS USING A COMBINATION COMPRISING BTK INHIBITORS
-
, (2019/06/17)
Disclosed herein is a method for the pre...
A according to lu tini and its key intermediate for the preparation of the new method (by machine translation)
-
, (2018/03/26)
The invention relates to a according to ...
330792-70-6 Process route
-
-
1623-95-6
4-phenoxybenzoyl chloride
-
-
109-77-3
malononitrile
-
-
330792-70-6
5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
| Conditions | Yield |
|---|---|
|
4-phenoxybenzoyl chloride; malononitrile;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 - 20 ℃;
for 1.5h;
Inert atmosphere;
Cooling with ice;
With
dimethyl sulfate;
In
tetrahydrofuran; mineral oil;
for 2h;
Reflux;
With
triethylamine; hydrazine;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 2h;
Reflux;
|
18%
|
-
-
1055710-57-0
2-[amino(4-phenoxyphenyl)methylene]malononitrile
-
-
330792-70-6
5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
methanol;
for 1h;
Reflux;
|
64%
|
330792-70-6 Upstream products
-
330792-69-3
2-[(4-phenoxy-phenyl)-methoxy-methylene]-malononitrile
-
1623-95-6
4-phenoxybenzoyl chloride
-
109-77-3
malononitrile
-
21218-94-0
methyl 4-phenoxybenzoate
330792-70-6 Downstream products
-
928309-79-9
C24 H19 BrN4 O
-
1207957-96-7
C25 H21 BrN4 O
-
928309-83-5
C25 H21 BrN4 O2
-
928309-86-8
C25 H21 BrN4 O2